CMSE 491/890: Bioinformatics & Computational Biology
CMSE 491/890: Bioinformatics & Computational BiologyJanuary 7, 2019 - 11:00am to May 3, 2019 - 12:15pm
Instructor: Dr. Arjun Krishnan
An introduction to contemporary topics, discussing the major biological/biomedical questions, exploring the relevant datasets, and understanding the underlying analytical approaches (from probability/statistics, applied mathematics, algorithms/data-structures, and data-science/machine-learning).
Note this course is open to both undergraduate (400-level) and graduate (800-level) students and counts towards the CMSE minor, garduate certificates, and dual PhD.
Through discussions of primary literature and a class project, students will also have the opportunity to learn how to: Formulate problems for quantitative inquiry • Design computational projects • Think critically about data & methods • Perform reproducible research • Communicate research findings.
Genome assembly & annotation • Sequence alignment & pattern finding • Comparative genomics • Genetic variation & quantitative genetics • Regulatory genomics • Functional genomics • Molecular & digital evolution • Molecular dynamics • Protein residue coupling & structure prediction • Modeling cellular pathways • Metabolomics & modeling metabolic flux • Large-scale biological networks
For more information visit the course website: https://github.com/krishnanlab/teaching/tree/master/2019-spring_compbio
CMSE 201 or CMSE 301-305 or equivalent with programming; Two semesters of introductory biology; Statistics at the level of STT 231 is strongly recommended.